Establishing outcome measures in early knee osteoarthritis
نویسندگان
چکیده
منابع مشابه
Early knee osteoarthritis
Concepts regarding osteoarthritis, the most common joint disease, have dramatically changed in the past decade thanks to the development of new imaging techniques and the widespread use of arthroscopy that permits direct visualisation of intra-articular tissues and structure. MRI and ultrasound allow the early detection of pre-radiographic structural changes not only in the peri-articular bone ...
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INTRODUCTION Knee osteoarthritis (OA) is a multi-factorial degenerative joint disaese resulting in pain and altered neuromuscular performance. Repetition and abnormal loading, combined with mechanical factors are attributed to the progression of knee OA [1,2], but the effects of repetitive weight bearing activity remain unclear. The cumulative knee adductor load (CKAL) is a parameter that repre...
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OBJECTIVE This study calculated knee contact forces (KCF) and its relations with knee external knee adduction moments (KAM) and/or flexion moments (KFM) during the stance phase of gait in patients with early osteoarthritis (OA), classified based on early joint degeneration on Magnetic Resonance Imaging (MRI). We aimed at assessing if altered KCF are already present in early structural degenerat...
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OBJECTIVE To predict, using clinical and qMRI data, the incidence of total knee replacement (TKR) during the long-term follow-up of knee osteoarthritis (OA) patients who formerly received chondroitin sulfate (CS) or placebo treatment. DESIGN A post hoc intention-to-treat analysis to evaluate the incidence of TKR was done on knee OA patients who had participated in a 12-month trial evaluating ...
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OBJECTIVE To determine the frequency of knee osteoarthritis in adult patients with Diabetes mellitus and its association with body mass index (BMI) in kg/m2 and waist circumference (WC). METHODS This is a cross-sectional comparative study at a tertiary hospital based in an industrial area of Karachi. Patient population comprised of all adult diabetic subjects. Clinical and demographic data wa...
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ژورنال
عنوان ژورنال: Nature Reviews Rheumatology
سال: 2019
ISSN: 1759-4790,1759-4804
DOI: 10.1038/s41584-019-0237-3